Detecting rare structural variation in evolving microbial populations from new sequence junctions using breseq
نویسندگان
چکیده
منابع مشابه
Detecting rare structural variation in evolving microbial populations from new sequence junctions using breseq
New mutations leading to structural variation (SV) in genomes-in the form of mobile element insertions, large deletions, gene duplications, and other chromosomal rearrangements-can play a key role in microbial evolution. Yet, SV is considerably more difficult to predict from short-read genome resequencing data than single-nucleotide substitutions and indels (SN), so it is not yet routinely iden...
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ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2015
ISSN: 1664-8021
DOI: 10.3389/fgene.2014.00468